Selective intra-arterial drug administration in a model of large vessel ischemia
نویسندگان
چکیده
منابع مشابه
Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration.
BACKGROUND AND PURPOSE This research was performed to determine whether a selective inhibitor of the calcium-dependent protease, calpain, could reduce ischemia-associated brain damage when peripherally administered after a vascular occlusion. METHODS A variation of the rat middle cerebral artery occlusion model was used. A range of doses of AK295 (a novel calpain inhibitor synthesized for thi...
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Intra-arterial Thrombolysis for Postoperative Digital Ischemia: A Case Report
OBJECTIVE Surgical repair of digital flexion deformities can result in vascular injuries threatening the viability of the affected digit. While uncommon, these injuries are reported to have a rate as high as 0.8% following palmo-digital fasciectomy for Dupuytren's disease. Late presentation of such vascular events pose a challenge, since taking the patient to the operating room does not guarant...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2015
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2014.10.015